Absence of the Basement Membrane Component Nidogen 2, but Not of Nidogen 1, Results in Increased Lung Metastasis in Mice

Nidogen 1 and 2 are ubiquitous basement membrane (BM) components. They show a divergent expression pattern in certain adult tissues with a prominent localization of nidogen 2 in blood vessel BMs. Deletion of either nidogen 1 or 2 in mice had no effect on BM formation, suggesting complementary functi...

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Bibliographic Details
Main Authors: Mokkapati, Sharada, Bechtel, Manuela, Reibetanz, Marion, Miosge, Nicolai, Nischt, Roswitha
Format: Artigo
Language:Inglês
Published: SAGE Publications 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351237/
https://ncbi.nlm.nih.gov/pubmed/22260998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155412436586
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