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Basement Membrane Deposition of Nidogen 1 but Not Nidogen 2 Requires the Nidogen Binding Module of the Laminin γ1 Chain

The nidogen-laminin interaction is proposed to play a key role in basement membrane (BM) assembly. However, though there are similarities, the phenotypes in mice lacking nidogen 1 and 2 (nidogen double null) differ to those of mice lacking the nidogen binding module (γ1III4) of the laminin γ1 chain....

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Detalhes bibliográficos
Main Authors: Mokkapati, Sharada, Fleger-Weckmann, Anja, Bechtel, Manuela, Koch, Manuel, Breitkreutz, Dirk, Mayer, Ulrike, Smyth, Neil, Nischt, Roswitha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023487/
https://ncbi.nlm.nih.gov/pubmed/21084308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149864
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