Compound Genetic Ablation of Nidogen 1 and 2 Causes Basement Membrane Defects and Perinatal Lethality in Mice

Nidogen 1 and 2 are basement membrane glycoproteins, and previous biochemical and functional studies indicate that they may play a crucial role in basement membrane assembly. While they show a divergent expression pattern in certain adult tissues, both have a similar distribution during development....

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Autores principales: Bader, Bernhard L., Smyth, Neil, Nedbal, Sabine, Miosge, Nicolai, Baranowsky, Anke, Mokkapati, Sharada, Murshed, Monzur, Nischt, Roswitha
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190363/
https://ncbi.nlm.nih.gov/pubmed/16024816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6846-6856.2005
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