A Long ncRNA Links Copy Number Variation to a Polycomb/Trithorax Epigenetic Switch in FSHD Muscular Dystrophy

Repetitive sequences account for more than 50% of the human genome. Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease associated with reduction in the copy number of the D4Z4 repeat mapping to 4q35. By an unknown mechanism, D4Z4 deletion causes an epigenetic switch leadi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Cabianca, Daphne S., Casa, Valentina, Bodega, Beatrice, Xynos, Alexandros, Ginelli, Enrico, Tanaka, Yujiro, Gabellini, Davide
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350859/
https://ncbi.nlm.nih.gov/pubmed/22541069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.035
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars