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FSHD: copy number variations on the theme of muscular dystrophy

In humans, copy number variations (CNVs) are a common source of phenotypic diversity and disease susceptibility. Facioscapulohumeral muscular dystrophy (FSHD) is an important genetic disease caused by CNVs. It is an autosomal-dominant myopathy caused by a reduction in the copy number of the D4Z4 mac...

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Autors principals: Cabianca, Daphne Selvaggia, Gabellini, Davide
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002039/
https://ncbi.nlm.nih.gov/pubmed/21149563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007028
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