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Plasticity and mTOR: Towards Restoration of Impaired Synaptic Plasticity in mTOR-Related Neurogenetic Disorders

Objective. To review the recent literature on the clinical features, genetic mutations, neurobiology associated with dysregulation of mTOR (mammalian target of rapamycin), and clinical trials for tuberous sclerosis complex (TSC), neurofibromatosis-1 (NF1) and fragile X syndrome (FXS), and phosphatas...

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Библиографические подробности
Главные авторы: Gipson, Tanjala T., Johnston, Michael V.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350854/
https://ncbi.nlm.nih.gov/pubmed/22619737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/486402
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