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Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

Reinforcement of actin stress fibers in response to mechanical stimulation depends on a posttranslational mechanism that requires the LIM protein zyxin. The C-terminal LIM region of zyxin directs the force-sensitive accumulation of zyxin on actin stress fibers. The N-terminal region of zyxin promote...

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Autors principals: Hoffman, Laura M., Jensen, Christopher C., Chaturvedi, Aashi, Yoshigi, Masaaki, Beckerle, Mary C.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350550/
https://ncbi.nlm.nih.gov/pubmed/22456508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1057
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