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Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes

Mechanical stimulation of fibroblasts induces changes in the actin cytoskeleton including stress fiber (SF) reinforcement and realignment. Here we characterize the nuclear response to mechanical stimulation (uniaxial cyclic stretch). Using fluorescence microscopy and quantitative image analysis we f...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Hoffman, Laura M., Smith, Mark A., Jensen, Christopher C., Yoshigi, Masaaki, Blankman, Elizabeth, Ullman, Katharine S., Beckerle, Mary C.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521858/
https://ncbi.nlm.nih.gov/pubmed/31967947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-01-0027
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