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Cobalt Cystathionine β-Synthase: A Cobalt-Substituted Heme Protein with a Unique Thiolate Ligation Motif
Human cystathionine β-synthase (hCBS), a key enzyme in the transsulfuration pathway, catalyzes the condensation of serine with homocysteine to produce cystathionine. CBS from higher organisms is unique in that it is the only known protein that binds pyridoxal-5′-phosphate (PLP) and heme. Intriguingl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350334/ https://ncbi.nlm.nih.gov/pubmed/21480614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic102586b |
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