Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene.
Topoisomerase I cleavage sites have been mapped in vivo on the Hsp70 heat shock gene of Drosophila melanogaster cells using the drug camptothecin. Topoisomerase I cleavage was only observed when the Hsp70 gene was transcriptionally active. Site-specific single-strand DNA cleavage by topoisomerase I...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1989
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.21.8495 |
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