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Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene.

Topoisomerase I cleavage sites have been mapped in vivo on the Hsp70 heat shock gene of Drosophila melanogaster cells using the drug camptothecin. Topoisomerase I cleavage was only observed when the Hsp70 gene was transcriptionally active. Site-specific single-strand DNA cleavage by topoisomerase I...

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Sonraí bibleagrafaíochta
Foilsithe in:Nucleic Acids Res
Príomhchruthaitheoirí: Kroeger, P E, Rowe, T C
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Oxford University Press 1989
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.21.8495
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