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Maximizing the Power of Genome-Wide Association Studies: A Novel Class of Powerful Family-Based Association Tests

For genome-wide association studies in family-based designs, a new, universally applicable approach is proposed. Using a modified Liptak’s method, we combine the p-value of the family-based association test (FBAT) statistic with the p-value for the Van Steen-statistic. The Van Steen-statistic is ind...

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Detalhes bibliográficos
Main Authors: Won, Sungho, Bertram, Lars, Becker, David, Tanzi, Rudolph E., Lange, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349940/
https://ncbi.nlm.nih.gov/pubmed/22582089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-009-9016-z
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