Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy–Weinberg equilibrium

Although the rapid advancements in high throughput genotyping technology have made genome-wide association studies possible, these studies remain an expensive undertaking, especially when considering the large sample sizes necessary to find the small to moderate effect sizes that define complex dise...

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Detaylı Bibliyografya
Asıl Yazarlar: Fardo, David W, Becker, K David, Bertram, Lars, Tanzi, Rudolph E, Lange, Christoph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796342/
https://ncbi.nlm.nih.gov/pubmed/19491930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.85
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