Lysophosphatidic Acid Induces Lymphangiogenesis and IL-8 Production in Vitro in Human Lymphatic Endothelial Cells

The bioactive phospholipid lysophosphatidic acid (LPA) and its receptors LPA(1-3) are aberrantly expressed in many types of human cancer. LPA has been reported to induce tumor cell proliferation, migration, and cytokine production. However, whether LPA exerts an effect on lymphatic endothelial cells...

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Main Authors: Mu, Hong, Calderone, Tiffany L., Davies, Michael A., Prieto, Victor G., Wang, Hua, Mills, Gordon B., Bar-Eli, Menashe, Gershenwald, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349835/
https://ncbi.nlm.nih.gov/pubmed/22465753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.003
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