Fully Humanized Neutralizing Antibodies to Interleukin-8 (ABX-IL8) Inhibit Angiogenesis, Tumor Growth, and Metastasis of Human Melanoma

Interleukin-8 (IL-8) has recently been shown to contribute to human melanoma progression by functioning as a mitogenic and angiogenic factor. In the present study, we investigated whether targeting IL-8 by a fully human anti-IL-8 antibody (ABX-IL8) could be a potential therapeutic strategy to contro...

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Detalhes bibliográficos
Main Authors: Huang, Suyun, Mills, Lisa, Mian, Badar, Tellez, Carmen, McCarty, Marya, Yang, X.-D., Gudas, Jean M., Bar-Eli, Menashe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850702/
https://ncbi.nlm.nih.gov/pubmed/12107097
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