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De Novo Peptide Design with C3a Receptor Agonist and Antagonist Activities: Theoretical Predictions and Experimental Validation()
Targeting the complement component 3a receptor (C3aR) with selective agonists or antagonists is believed to be a viable therapeutic option for several diseases such as stroke, heart attack, reper-fusion injuries, and rheumatoid arthritis. We designed a number of agonists, partial agonists, and antag...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349770/ https://ncbi.nlm.nih.gov/pubmed/22500977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201609k |
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