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New Compstatin Variants through Two De Novo Protein Design Frameworks
Two de novo protein design frameworks are applied to the discovery of new compstatin variants. One is based on sequence selection and fold specificity, whereas the other approach is based on sequence selection and approximate binding affinity calculations. The proposed frameworks were applied to a c...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872270/ https://ncbi.nlm.nih.gov/pubmed/20483343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.057 |
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