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New Compstatin Variants through Two De Novo Protein Design Frameworks

Two de novo protein design frameworks are applied to the discovery of new compstatin variants. One is based on sequence selection and fold specificity, whereas the other approach is based on sequence selection and approximate binding affinity calculations. The proposed frameworks were applied to a c...

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Hlavní autoři: Bellows, M.L., Fung, H.K., Taylor, M.S., Floudas, C.A., López de Victoria, A., Morikis, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872270/
https://ncbi.nlm.nih.gov/pubmed/20483343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.057
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