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Triggering of the dsRNA Sensors TLR3, MDA5, and RIG-I Induces CD55 Expression in Synovial Fibroblasts

BACKGROUND: CD55 (decay-accelerating factor) is a complement-regulatory protein highly expressed on fibroblast-like synoviocytes (FLS). CD55 is also a ligand for CD97, an adhesion-type G protein-coupled receptor abundantly present on leukocytes. Little is known regarding the regulation of CD55 expre...

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Auteurs principaux: Karpus, Olga N., Heutinck, Kirstin M., Wijnker, Paul J. M., Tak, Paul P., Hamann, Jörg
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349673/
https://ncbi.nlm.nih.gov/pubmed/22590509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035606
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