Single amino acid changes that alter the DNA sequence specificity of the DNA-[N6-adenine] methyltransferase (Dam) of bacteriophage T4.

Bacteriophage T4 codes for a DNA-[N6-adenine] methyltransferase (Dam) which recognizes primarily the sequence GATC in both cytosine- and hydroxymethylcytosine-containing DNA. Hypermethylating mutants, damh, exhibit a relaxation in sequence specificity, that is, they are readily able to methylate non...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Miner, Z, Schlagman, S L, Hattman, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1989
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334954/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2510127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.20.8149
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