Loading...
Conserved sequence motif DPPY in region IV of the phage T4 Dam DNA-[N6-adenine]-methyltransferase is important for S-adenosyl-L-methionine binding.
Comparison of the deduced amino acid sequences of DNA-[N6-adenine]-methyltransferases has revealed several conserved regions. All of these enzymes contain a DPPY [or closely related] motif. By site-directed mutagenesis of a cloned T4 dam gene, we have altered the first proline residue in this motif...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
1993
|
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331487/ https://ncbi.nlm.nih.gov/pubmed/8233814 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|