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Non-viral human beta defensin-3 expression in a bioengineered human skin tissue: a therapeutic alternative for infected wounds

The innate immune system differentially regulates the expression of host defense peptides to combat infection during wound healing. We enhanced the expression of a host defense peptide, human β defensin-3 (hBD-3), in keratinocytes to generate a three-dimensional biologic dressing to improve healing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gibson, Angela L., Thomas-Virnig, Christina L., Centanni, John M., Schlosser, Sandy J., Johnston, Colette E., Van Winkle, Kelly F., Szilagyi, Andrea, He, Li-Ke, Shankar, Ravi, Allen-Hoffmann, B. Lynn
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349450/
https://ncbi.nlm.nih.gov/pubmed/22564233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2012.00786.x
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