Inhibition of Multidrug-resistant Acinetobacter baumannii by Nonviral Expression of hCAP-18 in a Bioengineered Human Skin Tissue

When skin is compromised, a cascade of signals initiates the rapid repair of the epidermis to prevent fluid loss and provide defense against invading microbes. During this response, keratinocytes produce host defense peptides (HDPs) that have antimicrobial activity against a diverse set of pathogens...

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Detalhes bibliográficos
Main Authors: Thomas-Virnig, Christina L, Centanni, John M, Johnston, Colette E, He, Li-Ke, Schlosser, Sandy J, Van Winkle, Kelly F, Chen, Ruibing, Gibson, Angela L, Szilagyi, Andrea, Li, Lingjun, Shankar, Ravi, Allen-Hoffmann, B Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736055/
https://ncbi.nlm.nih.gov/pubmed/19190595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.289
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