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Heme oxygenase, a novel target for the treatment of hypertension and obesity?
Heme oxygenase (HO) is the rate-limiting enzyme in the metabolism of heme-releasing bioactive molecules carbon monoxide (CO), biliverdin, and iron, each with beneficial cardiovascular actions. Biliverdin is rapidly reduced to bilirubin, a potent antioxidant, by the enzyme biliverdin reductase, and i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349392/ https://ncbi.nlm.nih.gov/pubmed/22071158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00517.2011 |
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