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Heme oxygenase, a novel target for the treatment of hypertension and obesity?

Heme oxygenase (HO) is the rate-limiting enzyme in the metabolism of heme-releasing bioactive molecules carbon monoxide (CO), biliverdin, and iron, each with beneficial cardiovascular actions. Biliverdin is rapidly reduced to bilirubin, a potent antioxidant, by the enzyme biliverdin reductase, and i...

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Autors principals: Hosick, Peter A., Stec, David E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349392/
https://ncbi.nlm.nih.gov/pubmed/22071158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00517.2011
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