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Heme Oxygenase Inhibition Increases Blood Pressure in Pregnant Rats

BACKGROUND: During normal gestation, the placenta is a relatively hypoxic organ and, as such, is subject to significant oxidative stress. In the preeclamptic patient, inadequate remodeling of the maternal vasculature severely exacerbates placental oxidative stress, which has been shown to be an impo...

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Autors principals: George, Eric M., Hosick, Peter A., Stec, David E., Granger, Joey P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731822/
https://ncbi.nlm.nih.gov/pubmed/23553216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpt045
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