Sex specific effects of heme oxygenase-2 deficiency on renovascular hypertension

BACKGROUND: Heme oxygenase-2 (HO-2) is the main isoform responsible for the breakdown of heme and release of carbon monoxide (CO) in the vasculature. Vascular derived CO protects against excessive vasoconstriction due to agents such as angiotensin II (Ang II) and in states of deficiency of nitric ox...

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Autori principali: Stout, Jacob M., Gousset, Monette U., Drummond, Heather A., Gray, Will, Pruett, Brandon E., Stec, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783623/
https://ncbi.nlm.nih.gov/pubmed/23721883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jash.2013.04.004
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