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Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat

Tubuloglomerular feedback (TGF) stabilizes nephron function from minute to minute and adapts to different steady-state inputs to maintain this capability. Such adaptation inherently renders TGF less efficient at buffering long-term disturbances, but the magnitude of loss is unknown. We undertook the...

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Auteurs principaux: Thomson, Scott C., Rieg, Timo, Miracle, Cynthia, Mansoury, Hadi, Whaley, Jean, Vallon, Volker, Singh, Prabhleen
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349378/
https://ncbi.nlm.nih.gov/pubmed/21940401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00357.2011
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