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Regulation and function of the two-pore-domain (K2P) potassium channel Trek-1 in alveolar epithelial cells

Hyperoxia can lead to a myriad of deleterious effects in the lung including epithelial damage and diffuse inflammation. The specific mechanisms by which hyperoxia promotes these pathological changes are not completely understood. Activation of ion channels has been proposed as one of the mechanisms...

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Autors principals: Schwingshackl, Andreas, Teng, Bin, Ghosh, Manik, West, Alina Nico, Makena, Patrudu, Gorantla, Vijay, Sinclair, Scott E., Waters, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349376/
https://ncbi.nlm.nih.gov/pubmed/21949155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00078.2011
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