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Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease

The relationships between airway epithelial Cl(−) secretion-Na(+) absorption balance, airway surface liquid (ASL) homeostasis, and lung disease were investigated in selected transgenic mice. 1) To determine if transgenic overexpression of wild-type (WT) human CFTR (hCFTR) accelerated Cl(−) secretion...

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Detalhes bibliográficos
Main Authors: Grubb, B. R., O'Neal, W. K., Ostrowski, L. E., Kreda, S. M., Button, B., Boucher, R. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349361/
https://ncbi.nlm.nih.gov/pubmed/22003093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00083.2011
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