The differential effects of statins on the metastatic behaviour of prostate cancer

BACKGROUND: Although statins do not affect the incidence of prostate cancer (CaP), usage reduces the risk of clinical progression and mortality. Although statins are known to downregulate the mevalonate pathway, the mechanism by which statins reduce CaP progression is unknown. METHODS: Bone marrow s...

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Detalhes bibliográficos
Main Authors: Brown, M, Hart, C, Tawadros, T, Ramani, V, Sangar, V, Lau, M, Clarke, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349174/
https://ncbi.nlm.nih.gov/pubmed/22531631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.138
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