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Structural Transitions and Oligomerization along Polyalanine Fibril Formation Pathways from Computer Simulations

The results of a computer simulation study of the aggregation kinetics of a large system of model peptides with particular focus on the formation of intermediates are presented. Discontinuous molecular dynamic simulations were used in combination with our intermediate-resolution protein model, PRIME...

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Detalhes bibliográficos
Main Authors: Phelps, Erin M., Hall, Carol K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348993/
https://ncbi.nlm.nih.gov/pubmed/22411226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24052
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