Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima

TM0077 from Thermotoga maritima is a member of the carbohydrate esterase family 7 and is active on a variety of acetylated compounds, including cephalosporin C. TM0077 esterase activity is confined to short-chain acyl esters (C2-C3), and is optimal around 100°C and pH 7.5. The positional specificity...

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Main Authors: Levisson, Mark, Han, Gye Won, Deller, Marc C., Xu, Qingping, Biely, Peter, Hendriks, Sjon, Ten Eyck, Lynn F., Flensburg, Claus, Roversi, Pietro, Miller, Mitchell D., McMullan, Daniel, von Delft, Frank, Kreusch, Andreas, Deacon, Ashley M., van der Oost, John, Lesley, Scott A., Elsliger, Marc-André, Kengen, Servé W. M., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348966/
https://ncbi.nlm.nih.gov/pubmed/22411095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24041
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