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Catalytic activity is retained in the Tetrahymena group I intron despite removal of the large extension of element P5.

We have made sizeable internal deletions within the self-splicing group I intron of Tetrahymena thermophila. Deletions were made in a piecewise manner in order to remove secondary structural elements thought to be extraneous to the catalytic center of the molecule. The resulting deletion mutants ret...

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Pubblicato in:Nucleic Acids Res
Autori principali: Joyce, G F, van der Horst, G, Inoue, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1989
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334894/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2477801/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.19.7879
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