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A Tetrahymena intron nucleotide connected to the GTP/arginine site.

We have substituted all nucleotides at intron nucleotide 260 (N260) in transcripts related to the self-splicing Tetrahymena rRNA. Substitution slightly affects the binding and reaction of GTP with this group I catalytic center; kcat/Km varies over a three-fold range. The base of N260 therefore commu...

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Detalhes bibliográficos
Main Authors: Yarus, M, Levine, J, Morin, G B, Cech, T R
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC318427/
https://ncbi.nlm.nih.gov/pubmed/2674904
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