Immunogenicity and Protective Capacity of a Virosomal Respiratory Syncytial Virus Vaccine Adjuvanted with Monophosphoryl Lipid A in Mice

Respiratory Syncytial Virus (RSV) is a major cause of viral brochiolitis in infants and young children and is also a significant problem in elderly and immuno-compromised adults. To date there is no efficacious and safe RSV vaccine, partially because of the outcome of a clinical trial in the 1960s w...

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Hlavní autoři: Kamphuis, Tobias, Meijerhof, Tjarko, Stegmann, Toon, Lederhofer, Julia, Wilschut, Jan, de Haan, Aalzen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348902/
https://ncbi.nlm.nih.gov/pubmed/22590614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036812
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