Chemical synthesis and proinflammatory responses of monophosphoryl lipid A adjuvant candidates

Lipopolysaccharides (LPS), which are structural components of the outer surface membrane of Gram-negative bacteria, trigger innate immune responses through activation of Toll-like receptor 4 (TLR4). Such responses may be exploited for the development of adjuvants and in particular monophosphoryl lip...

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Bibliographic Details
Main Authors: Maiti, Kaustabh K., DeCastro, Michael, El-Sayed, Abu-Baker M. Abdel-Aal, Foote, Matthew I., Wolfert, Margreet A., Boons, Geert-Jan
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835315/
https://ncbi.nlm.nih.gov/pubmed/20228877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.200900973
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