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Agonistic and antagonistic properties of a Rhizobium sin-1 lipid A modified by an ether-linked lipid

LPS from Rhizobium sin-1 (R. sin-1) can antagonize the production of tumor necrosis factor alpha (TNF-α) by E. coli LPS in human monocytic cells. Therefore these compounds provide interesting leads for the development of therapeutics for the prevention or treatment of septic shock. Detailed structur...

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Detalhes bibliográficos
Main Authors: Vasan, Mahalakshmi, Wolfert, Margreet A., Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830616/
https://ncbi.nlm.nih.gov/pubmed/17581652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b704427e
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