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Agonistic and antagonistic properties of a Rhizobium sin-1 lipid A modified by an ether-linked lipid
LPS from Rhizobium sin-1 (R. sin-1) can antagonize the production of tumor necrosis factor alpha (TNF-α) by E. coli LPS in human monocytic cells. Therefore these compounds provide interesting leads for the development of therapeutics for the prevention or treatment of septic shock. Detailed structur...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830616/ https://ncbi.nlm.nih.gov/pubmed/17581652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b704427e |
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