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Phylogenetic evidence of a role for 5-hydroxymethyluracil-DNA glycosylase in the maintenance of 5-methylcytosine in DNA.

5-Hydroxymethyluracil (HmUra) is formed in DNA as a product of oxidative attack on the methyl group of thymine. It is also the product of the deamination of 5-hydroxymethylcytosine (HmCyt) which may be formed via oxidation of 5-methylcytosine (MeCyt). HmUra is removed from DNA by a DNA glycosylase w...

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Publicat a:Nucleic Acids Res
Autors principals: Boorstein, R J, Chiu, L N, Teebor, G W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1989
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2798122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.19.7653
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