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Phylogenetic evidence of a role for 5-hydroxymethyluracil-DNA glycosylase in the maintenance of 5-methylcytosine in DNA.

5-Hydroxymethyluracil (HmUra) is formed in DNA as a product of oxidative attack on the methyl group of thymine. It is also the product of the deamination of 5-hydroxymethylcytosine (HmCyt) which may be formed via oxidation of 5-methylcytosine (MeCyt). HmUra is removed from DNA by a DNA glycosylase w...

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Bibliografiska uppgifter
Huvudupphovsmän: Boorstein, R J, Chiu, L N, Teebor, G W
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC334874/
https://ncbi.nlm.nih.gov/pubmed/2798122
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