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Impaired B Cell Development and Function in the Absence of IκBNS()

IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon T cell receptor (TCR) signaling. Mice carrying a targeted gene disruption of IκBNS demonstrate dysregulation of cytokines in T cells, macrophages and dendritic cells. IκBNS mediates both posit...

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Autors principals: Touma, Maki, Keskin, Derin B., Shiroki, Fumiko, Saito, Ibuki, Koyasu, Shigeo, Reinherz, Ellis L., Clayton, Linda K.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348541/
https://ncbi.nlm.nih.gov/pubmed/21900180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002109
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