Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives

Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease and development, drug discovery, and regenerative medicine. However, it is important to identify factors that may impact the utility of hPSCs for these applications. In an unbiased analysis of 205 hPSC and 130 s...

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Hauptverfasser: Nazor, Kristopher L., Altun, Gulsah, Lynch, Candace, Tran, Ha, Harness, Julie V., Slavin, Ileana, Garitaonandia, Ibon, Müller, Franz-Josef, Wang, Yu-Chieh, Boscolo, Francesca S., Fakunle, Eyitayo, Dumevska, Biljana, Lee, Sunray, Park, Hyun Sook, Olee, Tsaiwei, D’Lima, Darryl D., Semechkin, Ruslan, Parast, Mana M., Galat, Vasiliy, Laslett, Andrew L., Schmidt, Uli, Keirstead, Hans S., Loring, Jeanne F., Laurent, Louise C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348513/
https://ncbi.nlm.nih.gov/pubmed/22560082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.02.013
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