Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives

Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease and development, drug discovery, and regenerative medicine. However, it is important to identify factors that may impact the utility of hPSCs for these applications. In an unbiased analysis of 205 hPSC and 130 s...

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Main Authors: Nazor, Kristopher L., Altun, Gulsah, Lynch, Candace, Tran, Ha, Harness, Julie V., Slavin, Ileana, Garitaonandia, Ibon, Müller, Franz-Josef, Wang, Yu-Chieh, Boscolo, Francesca S., Fakunle, Eyitayo, Dumevska, Biljana, Lee, Sunray, Park, Hyun Sook, Olee, Tsaiwei, D’Lima, Darryl D., Semechkin, Ruslan, Parast, Mana M., Galat, Vasiliy, Laslett, Andrew L., Schmidt, Uli, Keirstead, Hans S., Loring, Jeanne F., Laurent, Louise C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348513/
https://ncbi.nlm.nih.gov/pubmed/22560082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.02.013
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