Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function

Amyloid precursor protein (APP), the parent molecule to amyloid β peptide, is part of larger gene family with two mammalian homologues, amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2). Initial knock-out studies demonstrated that while single APP family gene dele...

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Bibliographic Details
Main Authors: Midthune, Brea, Tyan, Sheue-Houy, Walsh, Jessica J., Sarsoza, Floyd, Eggert, Simone, Hof, Patrick R., Dickstein, Dara L., Koo, Edward H.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348437/
https://ncbi.nlm.nih.gov/pubmed/22353605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.02.001
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