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Functional Role of the Sarcin-Ricin Loop of the 23S rRNA in the Elongation Cycle of Protein Synthesis

The sarcin-ricin loop (SRL) is one of the longest conserved sequences in the 23S rRNA. The SRL has been accepted as crucial for the activity of the ribosome because it is targeted by cytotoxins such as α-sarcin and ricin that completely abolish translation. Nevertheless, the precise functional role...

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Detaylı Bibliyografya
Asıl Yazarlar: Shi, Xinying, Khade, Prashant K., Sanbonmatsu, Karissa Y., Joseph, Simpson
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348345/
https://ncbi.nlm.nih.gov/pubmed/22459262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.016
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