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Functional Role of the Sarcin-Ricin Loop of the 23S rRNA in the Elongation Cycle of Protein Synthesis

The sarcin-ricin loop (SRL) is one of the longest conserved sequences in the 23S rRNA. The SRL has been accepted as crucial for the activity of the ribosome because it is targeted by cytotoxins such as α-sarcin and ricin that completely abolish translation. Nevertheless, the precise functional role...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shi, Xinying, Khade, Prashant K., Sanbonmatsu, Karissa Y., Joseph, Simpson
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348345/
https://ncbi.nlm.nih.gov/pubmed/22459262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.016
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