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Functional Role of the Sarcin-Ricin Loop of the 23S rRNA in the Elongation Cycle of Protein Synthesis

The sarcin-ricin loop (SRL) is one of the longest conserved sequences in the 23S rRNA. The SRL has been accepted as crucial for the activity of the ribosome because it is targeted by cytotoxins such as α-sarcin and ricin that completely abolish translation. Nevertheless, the precise functional role...

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Bibliografski detalji
Glavni autori: Shi, Xinying, Khade, Prashant K., Sanbonmatsu, Karissa Y., Joseph, Simpson
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348345/
https://ncbi.nlm.nih.gov/pubmed/22459262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.016
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