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Functional Role of the Sarcin-Ricin Loop of the 23S rRNA in the Elongation Cycle of Protein Synthesis

The sarcin-ricin loop (SRL) is one of the longest conserved sequences in the 23S rRNA. The SRL has been accepted as crucial for the activity of the ribosome because it is targeted by cytotoxins such as α-sarcin and ricin that completely abolish translation. Nevertheless, the precise functional role...

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מידע ביבליוגרפי
Main Authors: Shi, Xinying, Khade, Prashant K., Sanbonmatsu, Karissa Y., Joseph, Simpson
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348345/
https://ncbi.nlm.nih.gov/pubmed/22459262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.016
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