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Functional Role of the Sarcin-Ricin Loop of the 23S rRNA in the Elongation Cycle of Protein Synthesis
The sarcin-ricin loop (SRL) is one of the longest conserved sequences in the 23S rRNA. The SRL has been accepted as crucial for the activity of the ribosome because it is targeted by cytotoxins such as α-sarcin and ricin that completely abolish translation. Nevertheless, the precise functional role...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348345/ https://ncbi.nlm.nih.gov/pubmed/22459262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.03.016 |
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