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Menthol Suppresses Nicotinic Acetylcholine Receptor Functioning in Sensory Neurons via Allosteric Modulation

In this study, we have investigated how the function of native and recombinant nicotinic acetylcholine receptors (nAChRs) is modulated by the monoterpenoid alcohol from peppermint (−) menthol. In trigeminal neurons (TG), we found that nicotine (75 μM)-activated whole-cell currents through nAChRs wer...

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Détails bibliographiques
Auteurs principaux: Hans, M., Wilhelm, M., Swandulla, D.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348174/
https://ncbi.nlm.nih.gov/pubmed/22281529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chemse/bjr128
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