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Menthol Suppresses Nicotinic Acetylcholine Receptor Functioning in Sensory Neurons via Allosteric Modulation

In this study, we have investigated how the function of native and recombinant nicotinic acetylcholine receptors (nAChRs) is modulated by the monoterpenoid alcohol from peppermint (−) menthol. In trigeminal neurons (TG), we found that nicotine (75 μM)-activated whole-cell currents through nAChRs wer...

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Main Authors: Hans, M., Wilhelm, M., Swandulla, D.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348174/
https://ncbi.nlm.nih.gov/pubmed/22281529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chemse/bjr128
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