Peroxisome Proliferator–Activated Receptor-γ Agonists Prevent In Vivo Remodeling of Human Artery Induced by Alloreactive T Cells

BACKGROUND: Ligands activating the transcription factor peroxisome proliferator–activated receptor-γ (PPARγ) have antiinflammatory effects. Vascular rejection induced by allogeneic T cells can be responsible for acute and chronic graft loss. Studies in rodents suggest that PPARγ agonists may inhibit...

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Main Authors: Tobiasova, Zuzana, Zhang, Lufeng, Yi, Tai, Qin, Linfeng, Manes, Thomas D., Kulkarni, Sanjay, Lorber, Marc I., Rodriguez, Frederick C., Choi, Je-Min, Tellides, George, Pober, Jordan S., Kawikova, Ivana, Bothwell, Alfred L.M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347886/
https://ncbi.nlm.nih.gov/pubmed/21690493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.015396
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